Comorbidities such as cardiovascular disease, sleep apnea, or uncontrolled diabetes change priorities: reduce hypoglycemia risk, avoid volume depletion, and maintain glycemic targets that fit the procedures risk profile

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Semaglutide doses are measured in milligrams at much lower absolute amounts (0.25mg to 2.4mg weekly) compared to tirzepatide (2.5mg to 15mg weekly)
Not following the proper sequencepressing and holding the pen against the skin, waiting for the clicks, and confirming the indicator shows the dose is completecan result in incomplete dosing