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This phase is highly individualized and requires careful observation

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Regulation of Met metabolism in the liver In the liver, when the consumption of Met exceeds its average dietary intake, de novo synthesis of Met occurs via the transfer of a methyl group from methylene-THF first by methylene-THF reductase (MTHFR) and then by Met synthase (MS) to Hcy to form Met to make up the difference (8, 9) (Figure 2)

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