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CPAP is undoubtedly recognized as the gold standard treatment of OSA, although treatment adherence is often suboptimal (up to 80% of individuals with OSA fail to adhere), and it does not address the pathophysiological mechanisms governing its pathogenesis, especially for overweight/obese individuals [26]
Conversely, studies have shown that both patients and healthcare professionals are reluctant to initiate GLP-1RAs [11, 12], despite the guideline recommendations and the health benefits of these therapies, particularly for patients in need of weight loss and those with low estimated glomerular filtration rate [1]
What makes PHGG stand out is its clinical evidence base
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