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Although it appears to be well tolerated and potentially beneficial in improving cholesterol metabolism, pantethine is not a vitamin, and the decision to use pharmacological doses of pantethine to treat elevated blood cholesterol or triglycerides should only be made in collaboration with a qualified healthcare provider who provides appropriate follow up

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Nutrition 1997;13:752-4 [review]

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When iron overload intensifies, iron ions and calcium ions compete through calcium channels, leading to a decrease in calcium ion influx and causing contractile dysfunction