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We then performed untargeted metabolomics and found 1154 nonredundant metabolites in the BM microenvironment (Fig

Add GIP receptor activation, as Tirzepatide does, and you layer in improved insulin sensitivity, enhanced fat metabolism, and what appears to be reduced GI side effects compared to GLP-1-only approaches

stable at room temperature for short-term handling All materials are synthesized using state-of-the-art solid-phase peptide synthesis (SPPS) under ISO-certified laboratory conditions at Pepsynth Labs

However, unlike DEM which depleted GSH in a specific manner, these agents interact with sulfhydryls from proteins, leading to impairment of vital cell functions

Live virus neutralization assay The live virus neutralization assay was conducted in a 96-well plate as described in the Chinese Pharmacopoeia (2025 edition)