Key Research Properties: Small molecule NNMT (nicotinamide N-methyltransferase) inhibitor Modulates NAD+ metabolism and methylation capacity Studied in context of energy expenditure and metabolic regulation NNMT is upregulated in obesity
5-Amino-1MQ is a small-molecule NNMT inhibitor, chemically a methylquinolinium (5-amino-1-methylquinolinium) compound
The distinct microbiome profile of 5A-1MQ-treated mice was also supported by k-means clustering
Reported / Possible Side Effects Mild, anecdotal: Occasional reports of mild headache, transient jitteriness, or injection-site reactions
Medical Oversight As with all peptides, it's recommended to work with a healthcare provider, peptide specialist, or longevity clinic especially if you have insulin resistance, metabolic syndrome, or are on medications
Evidence signal Longevity research 6 source-backed citations are connected to this page