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Currently, there are some hypotheses supporting that patients with BD may have an altered histaminergic system, with upregulated histamine levels in manic phases and downregulated in depression, being their fluctuations closely related to other pathophysiological mechanisms [183]
this actually started when I was 47, but I procrastinated for 2 years before I decided to try TRT
* Ozempic for diabetes is subsidised in Singapore when prescribed for its approved indication (type 2 diabetes management)
Economic evaluations of non-pharmacological interventions and cost-of-illness studies in bipolar disorder: a systematic review
Such alterations may result in dysfunction or symptoms involving high energy-consuming organs such as the brain, liver, heart, and skeletal muscles (64)
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