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July 29, 2021
Improvement in insulin sensitivity The recent finding that GIP/GLP-1 receptor co-agonists like tirzepatide have superior efficacy compared to selective GLP-1 receptor agonists with respect to glycemic control as well as body weight has renewed interest in GIP [20], which previously was thought to be without any therapeutic potential
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The clinical development program was discontinued due to insufficient weight loss efficacy rather than safety concerns
Insulin Effect on Creatine Transport in Skeletal Muscle
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