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Sautin YY, Johnson RJ

Elevated expression of tumour necrosis factor alpha in cultured granulosa cells from women with endometriosis

Consult your provider if you experience severe or persistent nausea and vomiting that prevents adequate food or fluid intake, signs of pancreatitis including severe abdominal pain , vision changes or signs of diabetic retinopathy progression if you have diabetes, severe constipation lasting more than a week despite interventions, rapid heart rate or chest pain, or complete lack of appetite suppression or weight loss after reaching 1mg dose for at least four weeks

However, it proved ineffective and was discontinued for this use

The good news is that most symptoms are mild