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doi: 10.1681/ASN.2009040450 83 MarcinkowskaJMielczarekMSroczynskaPSroczynskiJLachowskaJSeniorKet al
IVs work better than foods, hydration, or supplements in pill or liquid form because they enter our bloodstream immediately and can completely bypass the digestive system
This research peptide blend combines tesamorelin (a stabilized GHRH analog) with ipamorelin (a selective GHS-R1a / ghrelin receptor agonist)
Contrave dampens this brain signal and makes eating fatty food or sugary food less satisfying (less pleasurable) and reduces the urge to comfort eat or crave these foods. Through this study, researchers make the case for a combined approach, using both gut hormone analogs like GLP-1s, and NB-ER at the same time, to treat obesity Combining NB-ER with GLP-1 makes mechanistic sense because GLP-1 primarily makes a person feel full faster and decreases hunger, while NB-ER reduces food cravings, Hussain explained
However, the main concern with oral delivery is bioavailability, or how much of the peptide is absorbed into the bloodstream after digestion
Lian Z, et al
