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J Biol Chem 2008;283:22186-92.ArticlePubMedPMC 93

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The trial escalation tables stepped the amount up on a monthly cadence, beginning in the low single-digit milligram range and only advancing once the prior level felt comfortable

2.3 Evidence from animal models and human cohorts Experimental models have revealed significant evidence that the gut microbiome can influence both motor and non-motor PD symptoms [51]

Maintenance Phase After the initial series, you can taper down to a maintenance schedule

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