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Glutamate is the most abundant neurotransmitter in the brain

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PLoS One Rosas HD, Chen YI, Doros G, Salat DH, Chen N, Kwong KK et al (2012) Alterations in brain transition metals in Huntington disease: an evolving and intricate story

Results Cryo-EM of full-length human CBS reveals a filamentous architecture We pursued the cryo-EM structure of full-length CBS initially using two constructs: one where an N-terminal His-tag was removed during purification (CBS FL ) and one with a permanent C-terminal His-tag (CBS FL-CHis ) (Supplementary Fig

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Here we summarize some of the most important achievements reached in this lively area of research