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In Marias case, reinforcing education with follow-up calls or nurse visits may have clarified her confusion about diet and emergency signs

[11] Tirzepatide is a prescription medication approved by the FDA for the treatment of type 2 diabetes (under the brand name Mounjaro) and chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity (under the brand name Zepbound)

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Hepatic transporter protein function is then decreased, which leads to both an increase in hepatic bile acid chelation and persistent inflammation

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The model was run over a 40-year time horizon to approximate a lifetime perspective, with 3-month cycles in the first year (to capture treatment response and discontinuation) and annual cycles thereafter