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In a highdose semaglutide trial (7.2 mg weekly), participants lost about 20.7% of body weight in 72 weeks, with a substantial portion achieving up to 25% weight loss

In a substudy of the diabetes program, fat mass reduction reached up to about 26%, and the proportion of lean mass lost was not unusually high compared with other major weight loss approaches

This is not the full PDF, just enough to show the rhythm

This data suggests that the ELF GSH level of the maintained adaptive response is calibrated to prevent the CS-induced depletion of GSH levels below basal levels

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The body prefers a steady supply to maintain an optimal "redox" balancethe state where antioxidants and free radicals are in equilibrium