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Pharmacokinetics & Metabolism Research shows that BPC-157 has a short biological half-lifetypically under 30 minutesand undergoes rapid enzymatic breakdown into smaller peptide fragments

The Fc domain not only provides steric protection against proteolytic enzymes but may also reduce immunogenicity by minimizing the generation of anti-drug antibodies

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Liu team has developed C-PROTAC, which offers a breakthrough strategy to address the aforementioned challenges