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In weight-management studies, severe allergic reactions occurred in 0.1% of people on tirzepatide and none on placebo

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Mediterranean-style and low-carbohydrate diets have good evidence for diabetes management according to NICE guideline NG28 [1] [12] Regular physical activity : Combining aerobic exercise with resistance training improves insulin sensitivity and helps maintain weight loss Behavioural support : Psychological interventions, such as cognitive behavioural therapy (CBT), can address emotional eating and help establish sustainable habits Sleep optimisation : Adequate sleep (79 hours) supports metabolic health and appetite regulation Alternative medications may be appropriate depending on your condition

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