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The Efficacy Numbers TRIUMPH-2 percent body weight change at 80 weeks: Placebo: 4.0% (9.3 lb) Retatrutide 4 mg: 12.7% (29.8 lb) Retatrutide 9 mg: 19.1% (45.4 lb) Retatrutide 12 mg: 20.8% (49.6 lb) TRIUMPH-2 A1C change from a baseline of 7.7%: Placebo: 0.2% 4 mg: 1.4% 9 mg: 1.6% 12 mg: 1.5% TRIUMPH-3 percent body weight change at 80 weeks: Placebo: 3.2% (7.7 lb) Retatrutide 9 mg: 21.6% (52.7 lb) Retatrutide 12 mg: 22.6% (55.8 lb) The T2D Gap Now Has a Third Data Point Ive been circling this question for three articles now, so let me put it all in one place

Experts say the drugs effects on dopamine signaling and brain inflammation could account for the benefits

GLP-1 therapy is typically a 12 to 18 month program, sometimes longer, with the goal of reaching a maintenance dose once you hit your target weight

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Safety information for semaglutide recommends that people with a personal or family history of some thyroid tumors shouldnt take semaglutide