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(PubMed) Vidal-Casariego A, Burgos-Pelaez R, Martinez-Faedo C, et al

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While the injectable route of administration in Semaglutide / Cyanocobalamin Injection bypasses the need for gastrointestinal absorption, patients receiving high-dose or long-term metformin therapy may have increased B12 requirements that should be considered when determining appropriate dosing

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Weight regain following discontinuation of these medications is common (Figure 2), with up to two-thirds of weight loss being regained within the first year 24