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Drugs 64 TaoufikE.KouroupiG.ZygogianniO.MatsasR
Mercury is conjugated to glutathione by the GST enzymes (GSTT1, GSTM1, or GSTP1)
Monosubstituted benzene derivatives can be hydroxylated at ortho-, meta- or para-positions but para-hydroxylated product is most common, e.g
By 1993, Yoshiko Sonoda successfully purified the human CYP51A1 protein from liver microsomes and demonstrated its catalytic activity upon reconstitution with NADPH cytochrome P450 reductase (3.20 mmol per mg of protein /min), identifying its molecular weight as approximately 53 kDa [12]
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