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As with any compounded medication, administration should be performed by qualified personnel familiar with sterile injection techniques and patient monitoring
IGF-1 Lr3 (Insulin-like Growth Factor-I Long R3) is an 83 amino acid analog of human IGF-I comprising the complete human IGF-I sequence with the substitution of an Arg for the Glu at position 3 (hence R3), as well as a 13 amino acid extension peptide at the N-terminus
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Importantly, mTOR inhibition (e.g., via rapamycin) helps maintain astrocytes in a protective state and reduces neuronal lipid peroxidation damage (Zhang et al., 2025c)
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