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Every dose drawn from that vial will be 22% weaker than intended

Patients with vitamin B12 deficiency and concurrent renal or hepatic disease may require increased doses or more frequent administration of methylcobalamin

One of the authors, Dr Andrew Hill of Liverpool Universitys pharmacology department, said: These low prices open the door to worldwide access to an essential medicine. The researchers also found that core patents on semaglutide were due to expire in 10 countries this year, including Brazil, China, India, South Africa, Turkey, Mexico and Canada from 21 March, opening the way to generic competition

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Accurate dosing depends on clear visibility and bubble-free measurement