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Patients with a personal or family history of medullary thyroid cancer, multiple endocrine neoplasia syndrome type 2, or pancreatitis may not be appropriate candidates, among other contraindications reviewed during consultation
Tirzepatide ODT contains the same active ingredient as injectable tirzepatide and is expected to share the same contraindication profile, though this formulation has not undergone clinical trials
Some protocols combine both, but this should only happen with medical supervision.
There is limited case law, of course, and low transparency, as technical problems have prevented the UPC registry from publishing many cases and rulings
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