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For nausea, antiemetics may provide short-term relief but should be used under healthcare professional guidance
Patients with type 2 diabetes already have a two- to threefold higher baseline risk of pancreatitis due to metabolic stress, dyslipidemia, and insulin resistance
Selecting agents predominantly based on safety and ease of monitoring makes sense
Third, we could not establish the dose-response relationship of GLP-1RAs on outcomes due to sample size limitations
Bit of Background These new classes of antiobesity medications (ie, the GLP-1 agonists and dual agonists), referred to in this article as weight management medications, arent really new.1-4 The basic science and pharmaceutical research and development to bring these to market began more than two decades ago when two scientists, Matthias Tschop, MD, and Richard DiMarchi, PhD, hypothesized that the actions of various gut hormones may offer safe and unprecedented weight loss
GLP-1s are primarily used to treat diabetes and obesity by mimicking hormones to regulate blood sugar and reduce appetite
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