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In colorectal cancer, NSUN2 enhances the stability of PHGDH mRNA through m5C methylation, thereby activating the SSP, increasing the intracellular NADH/NAD + and NADPH/NADP + ratios, reducing ROS levels and apoptosis, and promoting tumor cell survival and proliferation (105)

Due to its stability and potential systemic effects, BPC-157 continues to be a prominent focus of preclinical and clinical studies, highlighting its significance in regenerative medicine and related disciplines

Pezzola S, Antonini G, Geroni C, Beria I, Colombo M, Broggini M, Mongelli N, Leboffe L, MacArthur R, Mozzi AF, Federici G, Caccuri AM: Role of glutathione transferases in the mechanism of brostallicin activation

Combination of alanine and glutathione as targeting ligands of nanoparticles enhances cargo delivery into the cells of the neurovascular unit