This isn't just theoretical
Chin Med J 132(1):106108 Hu Y, Ma X (2021) Icariin treatment protects against gentamicin-induced ototoxicity via activation of the AMPK-SIRT3 pathway
In accordance with one embodiment, a method for increasing circulating and/or intracellular levels of glutathione includes administering an effective amount of S-acetyl-glutathione (SAG) in the form of delayed-release composition to raise the circulating levels of glutathione to achieve clinically beneficial effects
However, NCBSO and free BSO, which did not have GSH-responsive properties, did not show obvious cytotoxicity within the given concentration range
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