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Multiple large-scale observational studies and peer-reviewed analyses published in 2025 and 2026 have contributed substantially to this field

Demirta, A

2025;S01909622(25):00198207

Yamakoshi J, Sano A, Tokutake S, Saito M, Kikuchi M, Kubota Y, et al Oral intake of proanthocyanidin-rich extract from grape seeds improves chloasma Phytother Res

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Neither semaglutide nor lanifibranor significantly improved fibrosis stages