Together with IL-3, IGF-I stimulates differentiation and proliferation of myeloid cells and has been shown to regulate lymphopoiesis by stimulating proliferation and differentiation of T and B cells in lymphoid organs (Heemskerk et al.)
If you miss one week, simply resume your regular schedule the following week without doubling your dosethis maintains consistent drug accumulation
In addition to this, GLP-1 enhances the production of insulin
Both medications commonly cause gastrointestinal side effects including nausea, diarrhoea, and abdominal discomfort, which may be additive when used together, especially during semaglutide initiation
Sources Eli Lilly press release: Lilly's triple agonist, retatrutide, successful in two additional Phase 3 obesity trials, delivering significant improvements in weight and A1C
however, the current drugs are limited by the transient procedure and lack of useful methods for delaying disease progress