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Three new Cochrane reviews find evidence that GLP-1 drugs result in clinically meaningful weight loss, but industry-funded studies raise questions
Early treatment matters
Nausea ranged from approximately 11% at the lowest 1 mg dose to 64% in some intermediate-dose arms, with about 33% in the 9 mg fixed-dose (highest-efficacy) arm
Mech Ageing Dev 2001;122:4168
Manninen S, Silvennoinen S, Bendel P, Lankinen M, Schwab US, Sankilampi U
12, 2009, pp
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