Additionally, both substances may independently cause gastrointestinal discomfort, and their combination could potentially amplify these effects in susceptible individuals, though this has not been formally studied
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But its been shown over and over that whether youre training for strength or for endurance, as much as those antioxidants might lower the pain, they can also lower the gains (check out this study, this one, this detailed review on antioxidants in resistance training and this great review of antioxidants in endurance training)
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These GI side effects typically peak during the first 4-8 weeks and improve as your body adjusts to the medication
doi:10.1007/s00441-019-03016-8 (2) Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH