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Measurements around waist, hips, and other areas may continue decreasing during apparent plateaus as fat loss continues while muscle mass rebuilds

Nothing here is medical advice or a recommendation for human use, and improving insulin resistance may restore fertility, creating specific pregnancy-safety concerns that have not been studied for this compound

There is promising research suggesting that GLP-1 drugs may have a positive impact on fertility, particularly for women with insulin resistance and PCOS

The FDA approved Foundayo (orforglipron) in April 2026 as the first oral GLP-1 weight loss medication that can be taken with food at any time of day

Start by reviewing your Aetna drug formulary or speaking with your healthcare provider to find the best next step for your health and budget

however, several recent trials have informed updates to GDMT