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This makes it a vital nutrient for maintaining a high metabolic rate
GLP-1 has a short half-life of only two minutes, due to renal clearance and endogenous GLP-1 is degraded by the enzyme dipeptidyl peptidase IV (DPP-4) (2022)
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Lancet (2017) 390(10103):166475
The 72-hour rule counts hours, not calendar days
With a WL of only 12 kg being shown to increase subjective feelings of hunger, 20 and a WL of 0.8 kg associated with an increase in postprandial total ghrelin and a reduction in subjective feelings of fullness, 21 it is not surprising that adults find WL maintenance extremely hard
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