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In a randomized double-blind placebo-controlled study, participants consuming Reducose with sucrose (sugar) experienced significantly lower postprandial glucose and insulin responses compared to placebo
Surprisingly, another study showed that diabetes-related cardiovascular autonomic damage is first manifested in the vagus nerve (106), which may involve a ferroptosis-mediated overall decrease in parasympathetic tone, ultimately leading to over-activation of the sympathetic nerve and the worsening development of metabolic complications
doi: 10.1097/ALN.0000000000000320 21 JiaYGongNLiTFZhuBWangYX
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This is among the most well-studied drug classes in modern medicine
Results Study Selection and Characteristics A total of 23 phase III randomized controlled trials met the inclusion criteria, contributing 48 treatment arms conducted exclusively in individuals with T2DM (see Table 1 for a summary of trial-level and treatment-arm characteristics, and Supplementary Table S1 for detailed study characteristics)
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