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Patients should monitor for signs of hypoglycemia, especially if taking other glucose-lowering medications, and have a plan in place to quickly correct low blood sugar when needed (such as consuming glucose tablets or a fast-acting carbohydrate)

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Despite some negative effects on semen quality in men, fluoxetine has been shown to significantly improve intravaginal ejaculatory latency, ejaculatory control, and psychological distress in patients with primary premature ejaculation