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Schrch R, Todesco L, Novakova K, Mevissen M, Stieger B, Krhenbhl S

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Microbial genes, including cntA/B , the cai operon, and the gbu gene cluster, have been implicated in converting L-carnitine into TMA(O)

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While GHK has been shown to inhibit the inflammatory response and epithelial-mesenchymal transition (EMT) via the TGF-1/Smad 2/3 and IGF-1 pathways in bleomycin-induced fibrosis models [24], its broader anti-inflammatory effects in the context of pulmonary fibrosis pathogenesis may warrant further exploration

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Compounds such as chrysin, rutin, and proanthocyanins inhibit RAGE and suppress MAPK-induced SMAD 2/3 activation

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