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doi: 10.1042/BSR20160437 85 ZhangHMengJZhouSLiuYQuDWangLet al
People with higher starting body weight tend to lose a smaller percentage of their total weight compared to lighter individuals at the same dose, though they often lose more absolute pounds
Dehydration is particularly dangerous for people on certain blood pressure medications (like ACE inhibitors or diuretics) as it can put extra strain on the kidneys
Still, observable findings in study data typically follow a staged timeline: early physiological markers within the first one to two weeks, and measurable body-composition changes generally appearing over a four-to-eight-week research window
He emphasizes that the drug has the potential not just to stop the biological clock, but to literally turn it back