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The acute intraperitoneal glucose tolerance test (IPGTT) was performed in 8-week-old mice
Its core mechanism hinges on targeting the growth hormone secretagogue receptor (GHSR)
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LPS + l-carnitine + siRNA: siRNA pretreatment at 100 nM for 6 h in LPS-treated FLS, and 2.5 mM l-carnitine was administered for 24 h
This observation holds implications for the design and therapeutic use of positive GLP-1R allosteric modulators
