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However, the specific mechanism of GPx4 in the occurrence of breast cancer has not been elucidated and requires further study
Some preclinical work explores FOXO4-p53-targeting peptides against senescent cancer cells, and the developer has discussed cancer as a research interest, but there is no human evidence that FOXO4-DRI treats cancer
Catalytic mechanisms and specificities of glutathione peroxidases: variations of a basic scheme
Association of Vitamin B12 with Obesity, Overweight, Insulin Resistance and Metabolic Syndrome, and Body Fat Composition
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On the other hand, in cholestatic individuals in whom the NGS panels have not found pathogenic mutations, a comprehensive study like WES, performed over the full exome, can find potential gene candidates for a cholestasis association, as was the case with the most recently discovered PFIC, PFIC 13 [37, 90]
