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Phase 2 trial dosing used once-weekly subcutaneous injections with gradual escalation from 1 mg up to 12 mg to minimise gastrointestinal side effects

their primary role is induction of a negative energy balance

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Yes, some patients may notice worsening dry eye symptoms

Rationale and protocol of the Dapagliflozin And Prevention of Adverse outcomes in Chronic Kidney Disease (DAPA-CKD) randomized controlled trial

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