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More research is required
Both are synthetic 39-amino-acid incretin-receptor-agonist peptides, but Tirzepatide engages two receptors (GIPR, GLP-1R) while Retatrutide engages three (GIPR, GLP-1R, GCGR)
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The answer lies in gene expression
Single colonies were isolated and identified by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) using a Biotyper System (Bruker Daltonics Inc.) (64)
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