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Depressive state and chronic fatigue in multiple sclerosis and neuromyelitis optica
Previous studies at a dosage of up to 10 mg/kg caffeine showed no anxiolytic or anxiogenic effects in an open-field test and an elevated plus-maze test (Bhattacharya et al
When medication is stopped, appetite signals may return, and weight regain can occur when no maintenance strategy is in place
This demonstrates that without the medication, the bodys old patterns of hunger and metabolism tend to return
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