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MoriyamaTHigashiTTogashiKIidaTSegiESugimotoYet al

19,20 The other two meta-analyses failed to show a significant relationship

Researchers are still working to determine the optimal dose for addiction applications (which may differ from metabolic dosing), identify which patient subpopulations respond best, understand whether benefits persist after discontinuation, and characterize any unique risks of using these medications in populations with active substance use disorders

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This complex is essential for synapse formation, stabilization, and functional regulation, and its disruption has been strongly implicated in neurodevelopmental disorders such as ASD

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