6 Risk factors (hypertension, diabetes mellitus, smoking, and elevated lipids) cause both oxidative stress and minimal lesions at the high-pressure bifurcations of conducting vessels, which lead to an inflammatory response and the release of chemokines by endothelial cells
doi: 10.1093/annonc/mdz158
About 40% of patients with diabetes could develop CKD [4], and it could be already present at diagnosis especially in patients with type 2 diabetes [5]
The growth is evident irrespective of the parameters considered, and it indicates a shift from a conventional, older lifestyle to a contemporary, Western one
It should also serve to promote the growth of starter bacteria and deliver added functionalities like flavor generation
10.1016/j.ccr.2011.01.038 102 JansenR