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Iijima T, Shibuya M, Ito Y, Terauchi Y (2023) Effects of switching from liraglutide to semaglutide or dulaglutide in patients with type 2 diabetes: a randomized controlled trial
While previous studies have reviewed notable cutaneous adverse effects with other antidiabetic medications, little is known about GLP-1 agonist-induced cutaneous reactions
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Titration from 0.25mg to 0.5mg over 710 days allows receptor density to adjust, minimizing adverse events while building toward maintenance dosing of 0.51mg twice weekly
An increase in liver enzymes, and skin-related side effects, such as cutaneous hyperesthesia, have also been observed
The net benefit of GLP-1 receptor agonists in adults with overweight or obesity who do not have diabetes depends on their weight loss target and willingness to accept harms, according to researchers
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