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Severity and persistence vary
Factors influencing individual results include: Baseline metabolic health and insulin resistance Adherence to dietary and physical activity recommendations Genetic predisposition to weight loss Concurrent medications that may affect weight Psychological factors and eating behaviours Patients should maintain realistic expectations: whilst significant abdominal fat reduction is achievable, GLP-1 therapy will not produce a flat stomach or eliminate all belly fat, particularly in those with substantial weight to lose
[The findings] call into question the neurochemistry of these common mental health problems like depression and anxiety, he says
Headache You might feel a headache from the stress of withdrawal and dehydration, which can be remedied with lots of water throughout the day
Constipation and digestive changes Both tirzepatide and semaglutide slow gastric emptying, but they do so through somewhat different mechanisms
Individual factors and clinical context should guide any decisions
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