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Linear regression analysis was also performed to further identify the correlations between serum L-carnitine, TMAO levels, and MS in subjects with hyperglycemia, and the findings are presented in Table 7

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Supporting these clinical findings, animal studies have shown that intraperitoneal administration of LXA4 alleviates symptoms in EAE mice, reduces CD4 + and CD8 + T-cell infiltration into the CNS, and downregulates pathogenic effector subsets, such as Th1 and Th17 cells

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