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(PubMed) Lowik MR, van den Berg H, Kistemaker C, Brants HA, Brussaard JH

selective lipid metabolism modulation independent of GH receptor

When residues L43, W53, and F54 were substituted with alanine, the inhibitory ability was significantly reduced, indicating that these hydrophobic residues were essential for FOXO4 FHD binding (Table 1)

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Our research not only provides as a reference for future researches on the compatibility mechanism of other antidepressant traditional Chinese formulas, but also prepares for the high-throughput screening of antidepressant monomer compounds of TCM

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