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Further electrophysiological study showed that, opposite to the effects on arcuate POMC neurons, GLP-1 hyperpolarizes arcuate NPY neurons indirectly via increased GABA A receptor-mediated neurotransmission of local GABAergic interneurons (Secher et al., 2014

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Set Up Billing Verify your payer contracts cover obesity counseling/medication management Set up CPT codes for E/M visits and obesity counseling (if applicable) Train staff on GLP-1 prior authorization requirements (or use platform automation) Consider cash-pay pricing structure for patients without coverage 5

Dosage may be adjusted based on individual response