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Sivick, A.L
Heres how vitamin B12 injections can be particularly beneficial for our diverse patient population: Support for Patients with Malabsorption Disorders: Patients with conditions such as pernicious anemia or autoimmune disorders may struggle with the absorption of vitamin B12 due to a lack of intrinsic factors
doi:10.34172/ijoem.2020.1872
The constrained conformation additionally positions the pharmacophore residues (His, D-Phe, Arg, Trp) in an optimal spatial arrangement for simultaneous contact with the MC receptor binding pocket, which is why cyclic melanocortin analogs consistently demonstrate 10-100 fold greater potency than their linear counterparts in cAMP accumulation assays
This program doesnt do anything to influence clinical decision-making. Of course, a value-based program wouldnt necessarily turn to an expensive medication as the first tool it uses
BM: Conceptualization, Data curation, Investigation, Methodology, Writing original draft, Writing review & editing
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