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Unfortunately, a phase II clinical trial of UBX0101 (NCT03513016) was completed in patients with osteoarthritis and the promising results observed (Table 1), in vitro and in vivo, have not been up to the expectations in treated patients, leading only to a decrease of pain, without a significant improvement of the disease 30

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[2] In the US, non-prescription products can be purchased providing up to 1,000 g each, and it is a common ingredient in energy drinks and energy shots, usually at many times the recommended dietary allowance of B 12