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To determine whether arGSTs have such a modulating activity on LDOX, we ran two-step reactions, in which we separated At LDOX from the flavan-3,3,4-triol ( 4 ) product through ultrafiltration before addition of Ph AN9-clarified cell lysate
J Parkinsons Dis 5:821836
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In our in vivo studies with Tg2576 mice, we found that stereotactic delivery of adenoviral-Fbx2 to the brain significantly increased Fbx2 expression and decreased synaptic deficits coinciding with a reduction of BACE1, which is essential for A formation (Gong et al., 2010, 2013b)
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